E-ISSN 3041-4199
 
2025, Vol: 2, Issue: 1
2 / 1Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles

Original Article
Online Published: 22 Jan 2025
 


Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources

Nazeef Idris Usman, Ahmed Faruk Umar, Mahmud Yerima Iliyasu, Aminu Abdulwahab.


Abstract
Background and Aim
Silver nanoparticles (AgNPs) are recognized for their strong theragnostic properties and diverse applications in biomedical fields, including their effective use as antimicrobial agents. The study aimed to synthesize AgNPs using aqueous M. piperita extract and test its antibacterial activity against MDR-HvKp isolated from clinical sources.
Methods
The AgNPs were synthesized using M. piperita, physicochemical characterize EC, TDS, TDO, Ph, FTIR, and SEM. The antibacterial activity of M. piperita extract, AgNO3, and synthesized AgNPs was measured using the agar diffusion method, MIC, and MBC. Electrical conductivity of AgNPs (2130 µS/cm, normal range: 0-2500 µS/cm).
Results
Total dissolved solids (AgNPs: 768 ppm, normal range: 50-300 ppm), dissolved oxygen AgNPs: (3.20 mg/L, normal range: 6.5-8.0 mg/L), and pH, AgNPs: (7.0, normal range: 6.5-7.6). The AgNPs with size 400 nm (2.08 absorbance), after a 7days incubation period. The FTIR indicates AgNPs are capped with organic molecules, with peaks related to various organic functional groups such as C-H, C=O, and C-O are present. The SEM findings validated the production of spherical AgNPs with a crystalline structure and an average diameter of 20.42 nm. The M. piperita-AgNp conjugate record high MIC of 16mm(30 µg/ml) 14mm(25 µg/ml), 10mm(20 µg/ml) and 8mm(15 µg/ml). Followed by AgNPs with 6mm (30 µg/ml) and 4mm(15 µg/ml), whereas Mentha piperita records 10mm(30 µg/ml) and 4mm(15 µg/ml), with an MIC of 20µg/ml and MBC of 25µg/ml.
Conclusion
M. piperita's bioactive components enhance AgNP synthesis and antimicrobial activity against MDR-HvKp. Future research is needed to optimize component concentrations, synthesis parameters, and extraction methods for broader pathogen efficacy.

Key words: AgNPs, Antibacterial, Mentha piperita, MDR-HvKp


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Nazeef Idris Usman
Articles by Ahmed Faruk Umar
Articles by Mahmud Yerima Iliyasu
Articles by Aminu Abdulwahab
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Usman NI, Umar AF, Iliyasu MY, Abdulwahab A. Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. J Biol Res Rev. Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438

Web Style

Usman NI, Umar AF, Iliyasu MY, Abdulwahab A. Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. https://www.wisdomgale.com/jbrr/?mno=302657700 [Access: January 22, 2025]. doi:10.5455/JBRR.20240823083438

AMA (American Medical Association) Style

Usman NI, Umar AF, Iliyasu MY, Abdulwahab A. Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. J Biol Res Rev. Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


Vancouver/ICMJE Style

Usman NI, Umar AF, Iliyasu MY, Abdulwahab A. Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. J Biol Res Rev, [cited January 22, 2025]; Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


Harvard Style

Usman, N. I., Umar, . A. F., Iliyasu, . M. Y. & Abdulwahab, . A. (2025) Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. J Biol Res Rev, Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


Turabian Style

Usman, Nazeef Idris, Ahmed Faruk Umar, Mahmud Yerima Iliyasu, and Aminu Abdulwahab. 2025. Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. Journal of Biological Research and Reviews, Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


Chicago Style

Usman, Nazeef Idris, Ahmed Faruk Umar, Mahmud Yerima Iliyasu, and Aminu Abdulwahab. "Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources." Journal of Biological Research and Reviews Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


MLA (The Modern Language Association) Style

Usman, Nazeef Idris, Ahmed Faruk Umar, Mahmud Yerima Iliyasu, and Aminu Abdulwahab. "Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources." Journal of Biological Research and Reviews Online First: 22 Jan, 2025. Web. 22 Jan 2025 doi:10.5455/JBRR.20240823083438


APA (American Psychological Association) Style

Usman, N. I., Umar, . A. F., Iliyasu, . M. Y. & Abdulwahab, . A. (2025) Synthesis, Characterization, and antibacterial activity of Combine Mentha piperita - Silver nanoparticle on Multi-drug Resistant Hypervirulent Klebsiella pneumoniae from clinical sources. Journal of Biological Research and Reviews, Online First: 22 Jan, 2025. doi:10.5455/JBRR.20240823083438


Author LoginReviewer LoginAbout PublisherOpen Access PolicyEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Privacy PolicyCorrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesDigital Archiving & Preservation PoliciesTerms of UseLicense InformationCopyright Information

About Journal of Biological Research and Reviews

Journal of Biological Research and Reviews is an international, peer-reviewed, open access journal, providing a platform for advances in basic, translatio ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

Your comments are very important to us

We welcome your ideas, suggestions, comments, or questions. To reach Editorial Board please use one of the methods provided below.
 

Emails:

info@wisdomgale.com
editorinchief@ejmanager.com

Office Address:
WisdomGale Publishing
14 Rue de Grand-Bigard,
1082 Brussels
Belgium
 
We will respond within 48 to 72 hours.
 
Change of address or personal information? Please visit your account at www.ejmanager.com to update your information.